The Serum Profile of Hypercytokinemia Factors Identified in H7N9-Infected Patients can Predict Fatal Outcomes
نویسندگان
چکیده
Jing Guo1,2,*, Fengming Huang3,*, Jun Liu4,*, Yu Chen1,2,*, Wei Wang3,*, Bin Cao5,*, Zhen Zou3, Song Liu3, Jingcao Pan6, Changjun Bao7, Mei Zeng8, Haixia Xiao9, Hainv Gao1,2, Shigui Yang1,2, Yan Zhao3, Qiang Liu3, Huandi Zhou3, Jingdong Zhu3, Xiaoli Liu1,2, Weifeng Liang1,2, Yida Yang1,2, Shufa Zheng1,2, Jiezuan Yang1,2, Hongyan Diao1,2, Kunkai Su1,2, Li Shao1,2, Hongcui Cao1,2, Ying Wu10, Min Zhao10, Shuguang Tan10, Hui Li5, Xiaoqing Xu3, Chunmei Wang3, Jianmin Zhang3, Li Wang3, Jianwei Wang11, Jun Xu12, Dangsheng Li13, Nanshan Zhong12, Xuetao Cao3, George F Gao2,4,10,14, Lanjuan Li1,2 & Chengyu Jiang3
منابع مشابه
Corrigendum: The Serum Profile of Hypercytokinemia Factors Identified in H7N9-Infected Patients can Predict Fatal Outcomes.
The novel avian origin influenza A (H7N9) virus has caused severe diseases in humans in eastern China since the spring of 2013. Fatal outcomes of H7N9 infections are often attributed to the severe pneumonia and acute respiratory distress syndrome (ARDS). There is urgent need to discover biomarkers predicting the progression of disease and fatal outcome of potentially lethal flu infections, base...
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OBJECTIVE The present study aimed to analyze clinical features and factors associated with treatment outcomes of H7N9 influenza A virus infection. METHODS The clinical progress in 18 H7N9-infected patients was monitored and recorded. The clinical features of H7N9 infection were noted and factors associated with treatment outcomes were analyzed by univariate analyses. RESULTS The average age...
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Novel avian influenza A(H7N9) virus was isolated in fatal patients in Yangtze River Delta of China in March 2013. We aimed to screen the virus in febrile patients in a tertiary hospital in an area with confirmed cases. Throat-swab specimens collected from consecutive patients with fever (≥38°C) and flu-like symptoms from April 15 to April 25, 2013 were subjected to detect novel avian influenza ...
متن کاملEpidemiological and Clinical Characteristics and Risk Factors for Death of Patients with Avian Influenza A H7N9 Virus Infection from Jiangsu Province, Eastern China
BACKGROUND A novel avian influenza A (H7N9) virus has caused great morbidity as well as mortality since its emergence in Eastern China in February 2013. However, the possible risk factors for death are not yet fully known. METHODS AND FINDINGS Patients with H7N9 virus infection between March 1 and August 14, 2013 in Jiangsu province were enrolled. Data were collected with a standard form. Mea...
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A unique avian-origin A/H7N9 influenza virus has so far caused 134 cases with 44 deaths. Probing the host factors contributing to disease severity, we found that lower levels of plasma inflammatory cytokines on hospital admission correlated with faster recovery in 18 patients with A/H7N9 influenza virus, whereas high concentrations of (in particular) IL-6, IL-8, and macrophage inflammatory prot...
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